Storage and Handling for Meningococcal Vaccines

Proper vaccine storage and handling practices play an important role in protecting individuals and communities from vaccine-preventable diseases. For general recommendations and guidance, see Vaccine Storage and Handling. The guidance below is specific to meningococcal vaccines.

Temperature

• Store meningococcal vaccines (lyophilized and liquid components) in original packaging refrigerated between 2°C and 8°C (36°F and 46°F).
• Protect from light
• Do not freeze vaccine (lyophilized and liquid components) or expose to freezing temperatures. If the vaccine has been exposed to inappropriate conditions/temperatures or handled improperly:
  • Mark “Do NOT Use”
  • Isolate from other vaccines in a separate container
  • Store the vaccine at the appropriate temperature
  • Document details of the temperature excursion. Consult the vaccine manufacturer and/or your state or local immunization program for further guidance

Storage

• Store meningococcal vaccines in the original packaging.
  • For meningococcal vaccines that require reconstitution (Menveo, Penbraya, Penmenvy), store lyophilized and liquid components of the vaccine (which are packaged together) together in the refrigerator.

Reconstitution

• For meningococcal vaccines that require reconstitution (Menveo, Penbraya, Penmenvy), do NOT use if the reconstituted vaccine cannot be resuspended with agitation.
  • Only use the antigen-containing liquid component provided by the manufacturer to reconstitute the corresponding lyophilized component for the vaccine. Do not use any other diluent.
  • Never use stock vials of normal saline to reconstitute these vaccines.

Disposal

• Discard vaccine vials according to your state requirements for disposal.
• Medical waste disposal requirements are set by state environmental agencies. Contact the state or local immunization program or state environmental agency for guidance.