Appendix A

AIDS-Defining Conditions

• Bacterial infections, multiple or recurrent*
• Candidiasis of bronchi, trachea, or lungs
• Candidiasis of esophagus^†
• Cervical cancer, invasive^§
• Coccidioidomycosis, disseminated or extrapulmonary
• Cryptococcosis, extrapulmonary
• Cryptosporidiosis, chronic intestinal (>1 month's duration)
• Cytomegalovirus disease (other than liver, spleen, or nodes), onset at age >1 month
• Cytomegalovirus retinitis (with loss of vision)^†
• Encephalopathy, HIV related
• Herpes simplex: chronic ulcers (>1 month's duration) or bronchitis, pneumonitis, or esophagitis (onset at age >1 month)
• Histoplasmosis, disseminated or extrapulmonary
• Isosporiasis, chronic intestinal (>1 month's duration)
• Kaposi sarcoma^†
• Lymphoid interstitial pneumonia or pulmonary lymphoid hyperplasia complex*^†
• Lymphoma, Burkitt (or equivalent term)
• Lymphoma, immunoblastic (or equivalent term)
• Lymphoma, primary, of brain
• Mycobacterium avium complex or Mycobacterium kansasii, disseminated or extrapulmonary^†
• Mycobacterium tuberculosis of any site, pulmonary,^†§ disseminated,^† or extrapulmonary^†
• Mycobacterium, other species or unidentified species, disseminated^† or extrapulmonary^†
• Pneumocystis jirovecii pneumonia^†
• Pneumonia, recurrent^†§
• Progressive multifocal leukoencephalopathy
• Salmonella septicemia, recurrent
• Toxoplasmosis of brain, onset at age >1 month^†
• Wasting syndrome attributed to HIV

  * Only among children aged <13 years. (CDC. 1994 Revised classification system for human immunodeficiency virus infection in children less than 13 years of age. MMWR 1994;43[No. RR-12].)

  ^† Condition that might be diagnosed presumptively.

  ^§ Only among adults and adolescents aged >13 years. (CDC. 1993 Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR 1992;41[No. RR-17].)

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  Date last reviewed: 11/20/2008